منابع مشابه
Hepatic Encephalopathy: From the Pathogenesis to the New Treatments
Hepatic encephalopathy is a frequent and serious complication of liver cirrhosis; the pathophysiology of this complication is not fully understood although great efforts have been made during the last years. There are few prospective studies on the epidemiology of this complication; however, it is known that it confers with high short-term mortality. Hepatic encephalopathy has been classified i...
متن کاملNew strategies for treating hepatic encephalopathy.
blind, controlled study of glycerol phenylbutyrate in hepatic encephalopathy. Comment Hepatic encephalopathy (HE) is a serious neuro-psychiatric complication of both acute and chronic liver disease. Historically, the role of ammonia accumulation has dominated explanations of the patho-genesis of HE. However, evidence has emerged for a role of other concurrent factors such as inflammation , hypo...
متن کاملHepatic encephalopathy
Hepatic encephalopathy (HE) is a reversible syndrome of impaired brain function occurring in patients with advanced liver diseases. The precise pathophysiology of HE is still under discussion; the leading hypothesis focus on the role of neurotoxins, impaired neurotransmission due to metabolic changes in liver failure, changes in brain energy metabolism, systemic inflammatory response and altera...
متن کاملHepatic Encephalopathy
The liver is the most important organ for the well-functioning of other organs because of its vital role in nutrition, metabolism and secretion. Any disturbance in normal homeostasis of liver as it happens in acute liver failure (ALF) and chronic liver disease (cirrhosis) will lead to extra hepatic manifestations of liver disease, among them one is encephalopathy. And this encephalopathy caused...
متن کاملHepatic Encephalopathy
Hepatic encephalopathy (HE) is a brain disorder caused by chronic liver failure, particularly in alcoholics with cirrhosis, which results in cognitive, psychiatric, and motor impairments. In these patients, the number of functional liver cells is reduced, and some blood is diverted around the liver before toxins are removed. As a result, toxins such as ammonia and manganese can accumulate in th...
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ژورنال
عنوان ژورنال: Clinical Liver Disease
سال: 2015
ISSN: 2046-2484
DOI: 10.1002/cld.468